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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sigma intracellular receptor 2 | ||
| Ligand | BDBM50344429 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1884527 (CHEMBL4386109) | ||
| Ki | 2000±n/a nM | ||
| Citation |  Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety. J Med Chem62:4204-4217 (2019) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sigma intracellular receptor 2 | |||
| Name: | Sigma intracellular receptor 2 | ||
| Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 | ||
| Type: | Protein | ||
| Mol. Mass.: | 20953.88 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | Q5U3Y7 | ||
| Residue: | 176 | ||
| Sequence: |
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| BDBM50344429 | |||
| n/a | |||
| Name | BDBM50344429 | ||
| Synonyms: | CHEMBL1779993 | trans-N-Benzyl-3-methoxy-3,4-dihydrospiro-[[2]benzopyran-1,1'-cyclohexan]-4'-amine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H27NO2 | ||
| Mol. Mass. | 337.4553 | ||
| SMILES | COC1Cc2ccccc2[C@@]2(CC[C@@H](CC2)NCc2ccccc2)O1 |r,wU:10.26,wD:13.17,(24.78,6.63,;23.43,5.86,;23.43,4.32,;24.77,3.54,;24.76,2,;26.08,1.24,;26.08,-.29,;24.75,-1.06,;23.42,-.29,;23.43,1.24,;22.09,2,;21.33,.65,;19.6,1.28,;18.41,.86,;19.18,2.21,;20.82,1.59,;18.41,-.69,;19.75,-1.47,;19.74,-3.01,;18.4,-3.77,;18.39,-5.31,;19.72,-6.09,;21.06,-5.32,;21.07,-3.78,;22.09,3.54,)| | ||
| Structure | 
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