| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
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| Ligand | BDBM50065628 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1885429 (CHEMBL4387011) |
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| IC50 | 67±n/a nM |
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| Citation |  Luo, Z; Liu, H; Klein, RS; Tu, Z Design, synthesis, and in vitro bioactivity evaluation of fluorine-containing analogues for sphingosine-1-phosphate 2 receptor. Bioorg Med Chem27:3619-3631 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 2 |
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| Name: | Sphingosine 1-phosphate receptor 2 |
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| Synonyms: | EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38883.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay. |
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| Residue: | 353 |
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| Sequence: | MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
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| BDBM50065628 |
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| n/a |
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| Name | BDBM50065628 |
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| Synonyms: | CHEMBL1368758 | US9663511, Compound JTE013 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19Cl2N7O |
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| Mol. Mass. | 408.285 |
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| SMILES | CC(C)c1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)nc2n(C)nc(C)c12 |
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| Structure | 
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