| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Arginase |
|---|
| Ligand | BDBM50521942 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1885816 (CHEMBL4387398) |
|---|
| Ki | 5100±n/a nM |
|---|
| Citation |  Crizanto de Lima, E; Castelo-Branco, FS; Maquiaveli, CC; Farias, AB; Rennó, MN; Boechat, N; Silva, ER Phenylhydrazides as inhibitors of Leishmania amazonensis arginase and antileishmanial activity. Bioorg Med Chem27:3853-3859 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Arginase |
|---|
| Name: | Arginase |
|---|
| Synonyms: | n/a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36149.67 |
|---|
| Organism: | Leishmania amazonensis |
|---|
| Description: | ChEMBL_107995 |
|---|
| Residue: | 329 |
|---|
| Sequence: | MEHVQQYKFYKEKKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVF
DGKVVEARKASDNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGT
VAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPECFSWVPQVL
KPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMV
SYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHV
NDTISDGRAIARCMMGETLLYTPHTSSKL
|
|
|
|---|
| BDBM50521942 |
|---|
| n/a |
|---|
| Name | BDBM50521942 |
|---|
| Synonyms: | CHEMBL4216180 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H15F2N3O2 |
|---|
| Mol. Mass. | 319.306 |
|---|
| SMILES | CC(=O)Nc1ccccc1C(F)(F)C(=O)NNc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
