| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase |
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| Ligand | BDBM50521947 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1885817 (CHEMBL4387399) |
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| IC50 | 37000±n/a nM |
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| Citation |  Crizanto de Lima, E; Castelo-Branco, FS; Maquiaveli, CC; Farias, AB; Rennó, MN; Boechat, N; Silva, ER Phenylhydrazides as inhibitors of Leishmania amazonensis arginase and antileishmanial activity. Bioorg Med Chem27:3853-3859 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase |
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| Name: | Arginase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36149.67 |
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| Organism: | Leishmania amazonensis |
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| Description: | ChEMBL_107995 |
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| Residue: | 329 |
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| Sequence: | MEHVQQYKFYKEKKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVF
DGKVVEARKASDNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGT
VAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPECFSWVPQVL
KPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMV
SYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHV
NDTISDGRAIARCMMGETLLYTPHTSSKL
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| BDBM50521947 |
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| n/a |
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| Name | BDBM50521947 |
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| Synonyms: | CHEMBL4530523 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16F2N2O2 |
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| Mol. Mass. | 318.3179 |
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| SMILES | CC(=O)Nc1ccccc1C(F)(F)C(=O)NCc1ccccc1 |
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| Structure | 
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