| Reaction Details |
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 | Report a problem with these data |
| Target | Uracil-DNA glycosylase |
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| Ligand | BDBM50078341 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_212800 (CHEMBL816908) |
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| IC50 | 10000±n/a nM |
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| Citation |  Sun, H; Zhi, C; Wright, GE; Ubiali, D; Pregnolato, M; Verri, A; Focher, F; Spadari, S Molecular modeling and synthesis of inhibitors of herpes simplex virus type 1 uracil-DNA glycosylase. J Med Chem42:2344-50 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Uracil-DNA glycosylase |
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| Name: | Uracil-DNA glycosylase |
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| Synonyms: | DGU | UDG | UNG | UNG1 | UNG15 | UNG_HUMAN | Uracil-DNA glycosylase (UNG) |
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| Type: | Protein |
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| Mol. Mass.: | 34661.15 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P1305 |
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| Residue: | 313 |
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| Sequence: | MIGQKTLYSFFSPSPARKRHAPSPEPAVQGTGVAGVPEESGDAAAIPAKKAPAGQEEPGT
PPSSPLSAEQLDRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAE
ERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLE
NIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVS
WLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELL
QKSGKKPIDWKEL
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| BDBM50078341 |
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| n/a |
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| Name | BDBM50078341 |
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| Synonyms: | 1-(2-Hydroxy-ethyl)-6-(4-octyl-phenylamino)-1H-pyrimidine-2,4-dione | CHEMBL308968 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H29N3O3 |
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| Mol. Mass. | 359.4626 |
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| SMILES | CCCCCCCCc1ccc(Nc2cc(=O)[nH]c(=O)n2CCO)cc1 |
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| Structure | 
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