| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thiosulfate sulfurtransferase |
|---|
| Ligand | BDBM50063753 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1891102 (CHEMBL4392929) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Stevens, M; Abdeen, S; Salim, N; Ray, AM; Washburn, A; Chitre, S; Sivinski, J; Park, Y; Hoang, QQ; Chapman, E; Johnson, SM HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules. Bioorg Med Chem Lett29:1106-1112 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thiosulfate sulfurtransferase |
|---|
| Name: | Thiosulfate sulfurtransferase |
|---|
| Synonyms: | 2.8.1.1 | Rhodanese | THTR_HUMAN | TST | Thiosulfate sulfurtransferase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33432.06 |
|---|
| Organism: | Homo sapiens |
|---|
| Description: | ChEMBL_118080 |
|---|
| Residue: | 297 |
|---|
| Sequence: | MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFD
IEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFG
HRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLV
DSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDL
SQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
|
|
|
|---|
| BDBM50063753 |
|---|
| n/a |
|---|
| Name | BDBM50063753 |
|---|
| Synonyms: | CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide | N-{5-Chloro-4-[(4-chloro-phenyl)-cyano-methyl]-2-methyl-phenyl}-2-hydroxy-3,5-diiodo-benzamide | cid_42574 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H14Cl2I2N2O2 |
|---|
| Mol. Mass. | 663.074 |
|---|
| SMILES | Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
