| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thiosulfate sulfurtransferase |
|---|
| Ligand | BDBM26655 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1891102 (CHEMBL4392929) |
|---|
| IC50 | 330±n/a nM |
|---|
| Citation |  Stevens, M; Abdeen, S; Salim, N; Ray, AM; Washburn, A; Chitre, S; Sivinski, J; Park, Y; Hoang, QQ; Chapman, E; Johnson, SM HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules. Bioorg Med Chem Lett29:1106-1112 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thiosulfate sulfurtransferase |
|---|
| Name: | Thiosulfate sulfurtransferase |
|---|
| Synonyms: | 2.8.1.1 | Rhodanese | THTR_HUMAN | TST | Thiosulfate sulfurtransferase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33432.06 |
|---|
| Organism: | Homo sapiens |
|---|
| Description: | ChEMBL_118080 |
|---|
| Residue: | 297 |
|---|
| Sequence: | MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFD
IEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFG
HRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLV
DSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDL
SQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
|
|
|
|---|
| BDBM26655 |
|---|
| n/a |
|---|
| Name | BDBM26655 |
|---|
| Synonyms: | 2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-chromen-4-one | CHEMBL253570 | Gossypetin (23) | gossypetin |
|---|
| Type | Flavonoid |
|---|
| Emp. Form. | C15H10O8 |
|---|
| Mol. Mass. | 318.2351 |
|---|
| SMILES | Oc1ccc(cc1O)-c1oc2c(O)c(O)cc(O)c2c(=O)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
