| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50078792 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_38319 |
|---|
| IC50 | 440±n/a nM |
|---|
| Citation |  Mathvink, RJ; Barritta, AM; Candelore, MR; Cascieri, MA; Deng, L; Tota, L; Strader, CD; Wyvratt, MJ; Fisher, MH; Weber, AE Potent, elective human beta3 adrenergic receptor agonists containing a substituted indoline-5-sulfonamide pharmacophore. Bioorg Med Chem Lett9:1869-74 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46461.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07550 |
|---|
| Residue: | 413 |
|---|
| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
|
|
|
|---|
| BDBM50078792 |
|---|
| n/a |
|---|
| Name | BDBM50078792 |
|---|
| Synonyms: | 4-[methyl(4-octyl-1,3-thiazol-2-yl)amino]-N-phenylbenzene-1-sulfonamide | CHEMBL56767 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H31N3O2S2 |
|---|
| Mol. Mass. | 457.652 |
|---|
| SMILES | CCCCCCCCc1csc(n1)N(C)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
