| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuromedin-K receptor |
|---|
| Ligand | BDBM50524032 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1891594 (CHEMBL4393421) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Yamamoto, K; Inuki, S; Ohno, H; Oishi, S Scaffold hopping of fused piperidine-type NK3 receptor antagonists to reduce environmental impact. Bioorg Med Chem27:2019-2026 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuromedin-K receptor |
|---|
| Name: | Neuromedin-K receptor |
|---|
| Synonyms: | NK-3 receptor | NK-3R | NK3R | NK3R_HUMAN | NKR | Neurokinin 3 receptor | Neurokinin B receptor | Neurokinin-3 (NK-3) | Neuromedin-3 receptor (NK-3R) | Neuromedin-3 receptor (NK3) | Neuromedin-K receptor | Neuromedin-K receptor (NK-3 receptor) | Neuromedin-K receptor (NK3) | Neuromedin-K receptor(NK3R) | TAC3R | TACR3 | Tachykinin receptor 3 | Tachykinin receptor 3 (NK3) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52221.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P29371 |
|---|
| Residue: | 465 |
|---|
| Sequence: | MATLPAAETWIDGGGGVGADAVNLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGL
PVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVT
NYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIA
VDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPGRTLCFVQWPEG
PKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKM
MIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLN
KRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVVFDPNDADT
TRSSRKKRATPRDPSFNGCSRRNSKSASATSSFISSPYTSVDEYS
|
|
|
|---|
| BDBM50524032 |
|---|
| n/a |
|---|
| Name | BDBM50524032 |
|---|
| Synonyms: | CHEMBL4569878 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H18FN3O2 |
|---|
| Mol. Mass. | 387.4063 |
|---|
| SMILES | CC1N(CCc2c1noc2-c1ccc2ccccc2n1)C(=O)c1ccc(F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
