| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosinase |
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| Ligand | BDBM50219502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1892247 (CHEMBL4394168) |
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| IC50 | >1600±n/a nM |
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| Citation |  Husain, A; Khan, SA; Iram, F; Iqbal, MA; Asif, M Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore. Eur J Med Chem171:66-92 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosinase |
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| Name: | Tyrosinase |
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| Synonyms: | LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB |
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| Type: | Protein |
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| Mol. Mass.: | 60388.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14679 |
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| Residue: | 529 |
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| Sequence: | MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILL
SNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVR
RNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMH
YYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRD
AEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRN
PGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQS
SMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGH
NRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLG
AAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
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| BDBM50219502 |
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| n/a |
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| Name | BDBM50219502 |
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| Synonyms: | 4-hydroxyphenyl beta-D-glucopyranoside | Arbutin | CHEMBL232202 | hydroquinone O-beta-D-glucopyranoside | p-hydroxyphenyl beta-D-glucopyranoside | p-hydroxyphenyl beta-D-glucoside |
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| Type | Small organic molecule |
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| Emp. Form. | C12H16O7 |
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| Mol. Mass. | 272.2512 |
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| SMILES | OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r| |
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| Structure | 
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