| Reaction Details |
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 | Report a problem with these data |
| Target | Vesicular acetylcholine transporter |
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| Ligand | BDBM50039604 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_213559 (CHEMBL817829) |
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| Ki | 0.130000±n/a nM |
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| Citation |  Efange, SM; Khare, AB; Mach, RH; Parsons, SM Hydroxylated decahydroquinolines as ligands for the vesicular acetylcholine transporter: synthesis and biological evaluation. J Med Chem42:2862-9 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vesicular acetylcholine transporter |
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| Name: | Vesicular acetylcholine transporter |
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| Synonyms: | SLC18A3 | Solute carrier family 18 member 3 | VACHT | VACHT_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56900.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507628 |
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| Residue: | 532 |
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| Sequence: | MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
IAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESE
DVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFA
ARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAG
KRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTT
CNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYG
ALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV
YAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRS
ERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
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| BDBM50039604 |
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| n/a |
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| Name | BDBM50039604 |
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| Synonyms: | (+)-1''-(3-Iodo-benzyl)-4-phenyl-[1,3'']bipiperidinyl-4''-ol | (-)-1''-(3-Iodo-benzyl)-4-phenyl-[1,3'']bipiperidinyl-4''-ol | (3''R,4''R)-1''-(3-Iodo-benzyl)-4-phenyl-[1,3'']bipiperidinyl-4''-ol | CHEMBL1204210 | CHEMBL50880 | trans-1-(3-iodobenzyl)-3-(4-phenylpiperidin-1-yl)piperidin-4-ol |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29IN2O |
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| Mol. Mass. | 476.3936 |
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| SMILES | O[C@@H]1CCN(Cc2cccc(I)c2)C[C@H]1N1CCC(CC1)c1ccccc1 |
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| Structure | 
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