Reaction Details | |||
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Target | Sigma non-opioid intracellular receptor 1 | ||
Ligand | BDBM50032403 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1894399 (CHEMBL4396320) | ||
Kd | 2.9±n/a nM | ||
Citation | Thum, S; Schepmann, D; Ayet, E; Pujol, M; Nieto, FR; Ametamey, SM; Wünsch, B Tetrahydro-3-benzazepines with fluorinated side chains as NMDA and ? Eur J Med Chem177:47-62 (2019) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Sigma non-opioid intracellular receptor 1 | |||
Name: | Sigma non-opioid intracellular receptor 1 | ||
Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein | ||
Type: | Protein | ||
Mol. Mass.: | 25307.17 | ||
Organism: | Cavia porcellus (Guinea pig) | ||
Description: | Q60492 | ||
Residue: | 223 | ||
Sequence: |
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BDBM50032403 | |||
n/a | |||
Name | BDBM50032403 | ||
Synonyms: | (Pentazocine) 6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2 ,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol | (Pentazocine) 6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol | (pentazocine)2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid | 1,13-dimethyl-10-(3-methyl-2-butenyl)-(1R,9R,13R)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Pentazocine) | 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(15S)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol(Pentazocine) | 6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol | 6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol (pentazocine) | 6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol; lactate | CHEMBL100116 | PENTAZOCINE | PENTAZOCINE (+) | PENTAZOCINE (-) | ||
Type | Small organic molecule | ||
Emp. Form. | C19H27NO | ||
Mol. Mass. | 285.4238 | ||
SMILES | [#6]-[#6]1-[#6]-2-[#6]-c3ccc(-[#8])cc3C1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |TLB:16:15:1:10.4.3,9:10:1:15.13.14| | ||
Structure |