| Reaction Details |
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 | Report a problem with these data |
| Target | Imidazoleglycerol-phosphate dehydratase |
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| Ligand | BDBM50079735 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90659 (CHEMBL700890) |
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| IC50 | 840±n/a nM |
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| Citation |  Schweitzer, BA; Loida, PJ; Thompson-Mize, RL; CaJacob, CA; Hegde, SG Design and synthesis of beta-carboxamido phosphonates as potent inhibitors of imidazole glycerol phosphate dehydratase. Bioorg Med Chem Lett9:2053-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Imidazoleglycerol-phosphate dehydratase |
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| Name: | Imidazoleglycerol-phosphate dehydratase |
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| Synonyms: | HIS3 | HIS7_CRYNB | IGPD |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21976.83 |
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| Organism: | Cryptococcus neoformans |
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| Description: | ChEMBL_90660 |
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| Residue: | 202 |
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| Sequence: | MSERIASVERTTSETHISCTIDLDHIPGVTEQKINVSTGIGFLDHMFTALAKHGGMSLQL
QCKGDLHIDDHHTAEDCALALGEAFKKALGERKGIKRYGYAYAPLDESLSRAVIDISSRP
YFMCHLPFTREKVGDLSTEMVSHLLQSFAFAAGVTLHIDSIRGENNHHIAESAFKALALA
IRMAISRTGGDDVPSTKGVLAL
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| BDBM50079735 |
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| n/a |
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| Name | BDBM50079735 |
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| Synonyms: | (2-Hexanoylamino-3-[1,2,4]triazol-1-yl-propyl)-phosphonic acid | CHEMBL64769 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H21N4O4P |
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| Mol. Mass. | 304.2826 |
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| SMILES | CCCCCC(=O)NC(Cn1cncn1)CP(O)(O)=O |
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| Structure | 
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