| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50407517 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1895523 (CHEMBL4397558) |
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| EC50 | 25±n/a nM |
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| Citation |  Stanek, M; Picard, LP; Schmidt, MF; Kaindl, JM; Hübner, H; Bouvier, M; Weikert, D; Gmeiner, P Hybridization of ?-Adrenergic Agonists and Antagonists Confers G Protein Bias. J Med Chem62:5111-5131 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51338.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08588 |
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| Residue: | 477 |
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| Sequence: | MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
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| BDBM50407517 |
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| n/a |
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| Name | BDBM50407517 |
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| Synonyms: | (-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17NO3 |
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| Mol. Mass. | 211.2576 |
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| SMILES | CC(C)NC[C@H](O)c1ccc(O)c(O)c1 |
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| Structure | 
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