| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Inositol hexakisphosphate kinase 2 |
|---|
| Ligand | BDBM50525744 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1897996 (CHEMBL4400031) |
|---|
| Ki | 4880±n/a nM |
|---|
| Citation |  Wormald, MM; Ernst, G; Wei, H; Barrow, JC Synthesis and characterization of novel isoform-selective IP6K1 inhibitors. Bioorg Med Chem Lett29:0 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Inositol hexakisphosphate kinase 2 |
|---|
| Name: | Inositol hexakisphosphate kinase 2 |
|---|
| Synonyms: | 2.7.4.- | IHPK2 | IP6K2 | IP6K2_HUMAN | Inositol hexakisphosphate kinase 2 | InsP6 kinase 2 | InsP6K2 | P(i)-uptake stimulator | PiUS |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49188.38 |
|---|
| Organism: | Homo sapiens |
|---|
| Description: | ChEMBL_119238 |
|---|
| Residue: | 426 |
|---|
| Sequence: | MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
KFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHH
VLETEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTVEKKGNISSQLKHYNPWS
MKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQ
IRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLR
RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKERPEVVLDSDAEDLEDLSEESA
DESAGAYAYKPIGASSVDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLIDIVTEI
SEESGE
|
|
|
|---|
| BDBM50525744 |
|---|
| n/a |
|---|
| Name | BDBM50525744 |
|---|
| Synonyms: | CHEMBL4555782 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H22N8O2 |
|---|
| Mol. Mass. | 430.4625 |
|---|
| SMILES | COc1ccc2c(CCNc3nc(NCc4ccc(=O)[nH]c4)c4nc[nH]c4n3)c[nH]c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
