| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-gamma |
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| Ligand | BDBM50080524 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_197247 |
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| EC50 | 27±n/a nM |
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| Citation |  Dhar, A; Liu, S; Klucik, J; Berlin, KD; Madler, MM; Lu, S; Ivey, RT; Zacheis, D; Brown, CW; Nelson, EC; Birckbichler, PJ; Benbrook, DM Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids. J Med Chem42:3602-14 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-gamma |
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| Name: | Retinoic acid receptor RXR-gamma |
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| Synonyms: | Nr2b3 | RXRG_MOUSE | Retinoid X receptor gamma | Rxrg |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50900.28 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_196589 |
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| Residue: | 463 |
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| Sequence: | MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRTLSAVG
TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG
IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD
CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSSHEDMPVERIL
EAELAVEPKTESYGDMNVENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD
MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL
LRLPALRSIGLKCLEHLFFFKLIGDTPIDSFLMEMLETPLQIT
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| BDBM50080524 |
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| n/a |
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| Name | BDBM50080524 |
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| Synonyms: | 1-Isopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 4-ethoxycarbonyl-phenyl ester | CHEMBL120210 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H29NO4 |
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| Mol. Mass. | 395.4914 |
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| SMILES | CCOC(=O)c1ccc(OC(=O)c2ccc3N(CCC(C)(C)c3c2)C(C)C)cc1 |
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| Structure | 
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