| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM50081112 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_61325 |
|---|
| Ki | 6.3±n/a nM |
|---|
| Citation |  Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH New generation dopaminergic agents. 7. Heterocyclic bioisosteres that exploit the 3-OH-phenoxyethylamine D2 template. Bioorg Med Chem Lett9:2593-8 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 419 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM50081112 |
|---|
| n/a |
|---|
| Name | BDBM50081112 |
|---|
| Synonyms: | 4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazol-2-one | CHEMBL314174 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H17N3O2 |
|---|
| Mol. Mass. | 283.3251 |
|---|
| SMILES | O=c1[nH]c2cccc(OCCNCc3ccccc3)c2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
