| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM344 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157724 (CHEMBL763397) |
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| Ki | 43±n/a nM |
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| Citation |  Hultén, J; Andersson, HO; Schaal, W; Danielson, HU; Classon, B; Kvarnström, I; Karlén, A; Unge, T; Samuelsson, B; Hallberg, A Inhibitors of the C(2)-symmetric HIV-1 protease: nonsymmetric binding of a symmetric cyclic sulfamide with ketoxime groups in the P2/P2' side chains. J Med Chem42:4054-61 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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| BDBM344 |
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| n/a |
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| Name | BDBM344 |
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| Synonyms: | (3R,4S,5S,6R)-4,5-dihydroxy-2,7-bis({[3-(2-hydroxyethyl)phenyl]methyl})-3,6-bis(phenoxymethyl)-1,2,7-thiadiazepane-1,1-dione | CHEMBL337872 | Cyclic Sulfamide deriv. 22 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H42N2O8S |
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| Mol. Mass. | 662.792 |
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| SMILES | OCCc1cccc(CN2[C@H](COc3ccccc3)[C@H](O)[C@@H](O)[C@@H](COc3ccccc3)N(Cc3cccc(CCO)c3)S2(=O)=O)c1 |r| |
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| Structure | 
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