| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50526679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1900545 (CHEMBL4402767) |
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| Ki | 1.1±n/a nM |
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| Citation |  Schwalbe, T; Huebner, H; Gmeiner, P Development of covalent antagonists for ?1- and ?2-adrenergic receptors. Bioorg Med Chem27:2959-2971 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1_MOUSE | Adrb1 | Adrb1r | Beta-1 adrenergic recepto | Beta-1 adrenergic receptor | Beta-1 adrenoceptor | Beta-1 adrenoreceptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50507.75 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_105090 |
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| Residue: | 466 |
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| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPEPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGTTPPARLLEPWTGCNGGTTTVDSDSSLDEPGRQGFSSESKV
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| BDBM50526679 |
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| n/a |
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| Name | BDBM50526679 |
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| Synonyms: | CHEMBL4456301 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H36N2O4S2 |
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| Mol. Mass. | 516.716 |
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| SMILES | COc1cc(CCNC[C@H](O)COc2cccc3ccccc23)ccc1OCCCSSCCN |r| |
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| Structure | 
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