| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50526679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1900546 (CHEMBL4402768) |
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| Ki | 0.073000±n/a nM |
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| Citation |  Schwalbe, T; Huebner, H; Gmeiner, P Development of covalent antagonists for ?1- and ?2-adrenergic receptors. Bioorg Med Chem27:2959-2971 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50526679 |
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| n/a |
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| Name | BDBM50526679 |
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| Synonyms: | CHEMBL4456301 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H36N2O4S2 |
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| Mol. Mass. | 516.716 |
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| SMILES | COc1cc(CCNC[C@H](O)COc2cccc3ccccc23)ccc1OCCCSSCCN |r| |
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| Structure | 
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