| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50081676 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29889 (CHEMBL641960) |
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| Ki | 538±n/a nM |
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| Citation |  Xie, R; Li, AH; Ji, XD; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Selective A(3) adenosine receptor antagonists: water-soluble 3, 5-diacyl-1,2,4-trialkylpyridinium salts and their oxidative generation from dihydropyridine precursors. J Med Chem42:4232-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50081676 |
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| n/a |
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| Name | BDBM50081676 |
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| Synonyms: | 4-(2-Acetylsulfanyl-ethyl)-2-ethyl-3-ethylsulfanylcarbonyl-1-methyl-6-phenyl-5-propoxycarbonyl-pyridinium; iodide | CHEMBL274501 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H32NO4S2 |
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| Mol. Mass. | 474.655 |
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| SMILES | CCCOC(=O)c1c(CCSC(C)=O)c(C(=O)SCC)c(CC)[n+](C)c1-c1ccccc1 |
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| Structure | 
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