| Reaction Details |
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 | Report a problem with these data |
| Target | Superoxide dismutase [Cu-Zn] |
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| Ligand | BDBM50526703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1900857 (CHEMBL4403079) |
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| IC50 | >50000±n/a nM |
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| Citation |  Paucar, R; Martín-Escolano, R; Moreno-Viguri, E; Azqueta, A; Cirauqui, N; Marín, C; Sánchez-Moreno, M; Pérez-Silanes, S Rational modification of Mannich base-type derivatives as novel antichagasic compounds: Synthesis, in vitro and in vivo evaluation. Bioorg Med Chem27:3902-3917 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Superoxide dismutase [Cu-Zn] |
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| Name: | Superoxide dismutase [Cu-Zn] |
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| Synonyms: | SOD1 | SODC_HUMAN | Superoxide dismutase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 15933.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1444880 |
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| Residue: | 154 |
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| Sequence: | MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTS
AGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVV
HEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
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| BDBM50526703 |
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| n/a |
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| Name | BDBM50526703 |
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| Synonyms: | CHEMBL4475359 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21F3N2O2 |
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| Mol. Mass. | 378.3881 |
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| SMILES | Oc1ccc(cc1)C(=O)CCN1CCN(CC1)c1ccc(cc1)C(F)(F)F |
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| Structure | 
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