| Reaction Details |
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 | Report a problem with these data |
| Target | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
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| Ligand | BDBM176764 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1902008 (CHEMBL4404230) |
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| IC50 | 2000±n/a nM |
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| Citation |  Peterková, L; Kmoní?ková, E; Ruml, T; Rimpelová, S Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective. J Med Chem63:1937-1963 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
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| Name: | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
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| Synonyms: | 7.2.2.10 | AT2A3_HUMAN | ATP2A3 | Calcium pump 3 | SERCA3 | SR Ca(2+)-ATPase 3 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 109240.88 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_10715 |
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| Residue: | 999 |
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| Sequence: | MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL
LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK
EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL
TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA
AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR
KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT
SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML
DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD
LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI
GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA
LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT
PLSGRQWVVVLQISLPVILLDEALKYLSRNHMHEEMSQK
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| BDBM176764 |
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| n/a |
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| Name | BDBM176764 |
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| Synonyms: | 2,5-Di-tert-butylhydroquinone | CAS# 88-58-4 | US9688816, 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H22O2 |
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| Mol. Mass. | 222.3233 |
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| SMILES | CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C |
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| Structure | 
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