| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 |
|---|
| Ligand | BDBM29608 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1902017 (CHEMBL4404239) |
|---|
| IC50 | 2000±n/a nM |
|---|
| Citation |  Peterková, L; Kmoní?ková, E; Ruml, T; Rimpelová, S Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective. J Med Chem63:1937-1963 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 |
|---|
| Name: | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 |
|---|
| Synonyms: | AT2A2_RAT | Atp2a2 | Calcium pump 2 | Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform | Endoplasmic reticulum class 1/2 Ca(2+) ATPase | SERCA2 | SR Ca(2+)-ATPase 2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 114748.59 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_109815 |
|---|
| Residue: | 1043 |
|---|
| Sequence: | MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVQKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECAQPATKPSCSLSACTDGISWPFV
LLIMPLVVWVYSTDTNFSDMFWS
|
|
|
|---|
| BDBM29608 |
|---|
| n/a |
|---|
| Name | BDBM29608 |
|---|
| Synonyms: | Bisphenol A (BPA) | Diphenylolpropane | US9688816, L |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H16O2 |
|---|
| Mol. Mass. | 228.2863 |
|---|
| SMILES | CC(C)(c1ccc(O)cc1)c1ccc(O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
