| Reaction Details |
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 | Report a problem with these data |
| Target | Urokinase-type plasminogen activator |
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| Ligand | BDBM50082182 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_155744 (CHEMBL760894) |
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| Ki | 73000±n/a nM |
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| Citation |  Stürzebecher, J; Vieweg, H; Steinmetzer, T; Schweinitz, A; Stubbs, MT; Renatus, M; Wikström, P 3-Amidinophenylalanine-based inhibitors of urokinase. Bioorg Med Chem Lett9:3147-52 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Urokinase-type plasminogen activator |
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| Name: | Urokinase-type plasminogen activator |
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| Synonyms: | 3.4.21.73 | PLAU | U-plasminogen activator | UROK_HUMAN | Urokinase | Urokinase-type plasminogen activator (uPA) | Urokinase-type plasminogen activator chain B | Urokinase-type plasminogen activator long chain A | Urokinase-type plasminogen activator short chain A | Urokinase-type plasminogen activator/surface receptor | uPA |
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| Type: | Enzyme |
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| Mol. Mass.: | 48528.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00749 |
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| Residue: | 431 |
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| Sequence: | MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
SHTKEENGLAL
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| BDBM50082182 |
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| n/a |
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| Name | BDBM50082182 |
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| Synonyms: | 3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-pyrrolidin-1-yl-propyl]-benzamidine | CHEMBL106869 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26N4O3S |
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| Mol. Mass. | 450.553 |
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| SMILES | NC(=N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCC2)c1 |
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| Structure | 
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