| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Free fatty acid receptor 3 |
|---|
| Ligand | BDBM50527501 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1902640 (CHEMBL4404862) |
|---|
| EC50 | 251±n/a nM |
|---|
| Citation |  Ulven, ER; Quon, T; Sergeev, E; Barki, N; Brvar, M; Hudson, BD; Dutta, P; Hansen, AH; Bielefeldt, LŲ; Tobin, AB; McKenzie, CJ; Milligan, G; Ulven, T Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators. J Med Chem63:3577-3595 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Free fatty acid receptor 3 |
|---|
| Name: | Free fatty acid receptor 3 |
|---|
| Synonyms: | FFAR3 | FFAR3_HUMAN | GPR41 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38655.15 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1508992 |
|---|
| Residue: | 346 |
|---|
| Sequence: | MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTAS
DLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHP
LWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI
LLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGP
YNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQ
WQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
|
|
|
|---|
| BDBM50527501 |
|---|
| n/a |
|---|
| Name | BDBM50527501 |
|---|
| Synonyms: | CHEMBL4442868 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H20Cl2N2O2 |
|---|
| Mol. Mass. | 391.291 |
|---|
| SMILES | CC1=C(C(C2CC2)C2=C(CCCC2=O)N1)C(=O)Nc1cc(Cl)ccc1Cl |t:1,8| |
|---|
| Structure | 
|
|---|
Search and Browse
