| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
|---|
| Ligand | BDBM50084051 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_140050 |
|---|
| IC50 | 4180±n/a nM |
|---|
| Citation |  Rádl, S; Hezký, P; Hafner, W; Budesínský, M; Hejnová, L Synthesis and binding studies of some epibatidine analogues. Bioorg Med Chem Lett10:55-8 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M2 |
|---|
| Name: | Muscarinic acetylcholine receptor M2 |
|---|
| Synonyms: | ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51555.53 |
|---|
| Organism: | RAT |
|---|
| Description: | P10980 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRI
VKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
|
|
|
|---|
| BDBM50084051 |
|---|
| n/a |
|---|
| Name | BDBM50084051 |
|---|
| Synonyms: | 3-(6-Chloro-pyridin-3-yl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene; compound with (Z)-but-2-enedioic acid | CHEMBL345233 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H15ClN2 |
|---|
| Mol. Mass. | 234.725 |
|---|
| SMILES | CN1C2CCC1C=C(C2)c1ccc(Cl)nc1 |c:7,THB:9:7:1:4.3| |
|---|
| Structure | 
|
|---|
Search and Browse
