| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
|---|
| Ligand | BDBM50529733 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1909754 (CHEMBL4412200) |
|---|
| IC50 | 39±n/a nM |
|---|
| Citation |  Chen, D; Chen, Y; Lian, F; Chen, L; Li, Y; Cao, D; Wang, X; Chen, L; Li, J; Meng, T; Huang, M; Geng, M; Shen, J; Zhang, N; Xiong, B Fragment-based drug discovery of triazole inhibitors to block PDE?-RAS protein-protein interaction. Eur J Med Chem163:597-609 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
|---|
| Name: | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
|---|
| Synonyms: | 3',5'-cyclic phosphodiesterase | GMP-PDE delta | PDE6D | PDE6D_HUMAN | PDED | Protein p17 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 17418.30 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_105761 |
|---|
| Residue: | 150 |
|---|
| Sequence: | MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVS
RELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPA
SVLTGNVIIETKFFDDDLLVSTSRVRLFYV
|
|
|
|---|
| BDBM50529733 |
|---|
| n/a |
|---|
| Name | BDBM50529733 |
|---|
| Synonyms: | CHEMBL4585643 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H32N4OS |
|---|
| Mol. Mass. | 532.698 |
|---|
| SMILES | CC(C)Cc1nnc(SCc2ccc(cc2)C(=O)Nc2ccc(cc2)-c2ccccc2)n1Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
