| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM50085395 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_48998 |
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| Ki | 59±n/a nM |
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| Citation |  Gong, Y; Pauls, HW; Spada, AP; Czekaj, M; Liang, G; Chu, V; Colussi, DJ; Brown, KD; Gao, J Amido-(propyl and allyl)-hydroxybenzamidines: development of achiral inhibitors of factor Xa. Bioorg Med Chem Lett10:217-21 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | Activated coagulation factor X (FXa) | Activated factor Xa heavy chain | Coagulation factor X precursor | Coagulation factor Xa | F10 | FA10_HUMAN | Factor X heavy chain | Factor X light chain | Factor Xa | Stuart factor | Stuart-Prower factor |
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| Type: | Enzyme |
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| Mol. Mass.: | 54726.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 488 |
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| Sequence: | MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
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| BDBM50085395 |
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| n/a |
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| Name | BDBM50085395 |
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| Synonyms: | 4-tert-Butyl-N-[3-(5-carbamimidoyl-2-hydroxy-phenyl)-propyl]-benzamide | CHEMBL70741 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27N3O2 |
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| Mol. Mass. | 353.458 |
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| SMILES | CC(C)(C)c1ccc(cc1)C(=O)NCCCc1cc(ccc1O)C(N)=N |
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| Structure | 
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