| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50085430 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90573 (CHEMBL702430) |
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| IC50 | 75000±n/a nM |
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| Citation |  Singh, SB; Felock, P; Hazuda, DJ Chemical and enzymatic modifications of integric acid and HIV-1 integrase inhibitory activity. Bioorg Med Chem Lett10:235-8 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50085430 |
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| n/a |
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| Name | BDBM50085430 |
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| Synonyms: | (1S,4R,8aR)-4-((E)-2,4-Dimethyl-oct-2-enoyloxy)-8a-methyl-7-(1-methyl-allylidene)-6-oxo-1,2,3,4,6,7,8,8a-octahydro-naphthalene-1-carboxylic acid | CHEMBL308870 | CHEMBL76319 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H36O5 |
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| Mol. Mass. | 428.561 |
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| SMILES | CCCCC(C)\C=C(/C)C(=O)O[C@@H]1CC[C@H](C(O)=O)[C@@]2(C)CC(=C(C)C=C)C(=O)C=C12 |w:23.23,t:29| |
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| Structure | 
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