Reaction Details |
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Target | Translocator protein |
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Ligand | BDBM50408728 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1912567 (CHEMBL4415150) |
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Ki | 1.6±n/a nM |
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Citation | Vanda, D; Zajdel, P; Soural, M Imidazopyridine-based selective and multifunctional ligands of biological targets associated with psychiatric and neurodegenerative diseases. Eur J Med Chem181:0 (2019) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Translocator protein |
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Name: | Translocator protein |
Synonyms: | BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN |
Type: | Enzyme |
Mol. Mass.: | 18834.74 |
Organism: | Homo sapiens (Human) |
Description: | P30536 |
Residue: | 169 |
Sequence: | MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
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BDBM50408728 |
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n/a |
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Name | BDBM50408728 |
Synonyms: | CHEMBL339816 |
Type | Small organic molecule |
Emp. Form. | C21H25ClN4O |
Mol. Mass. | 384.902 |
SMILES | CCCN(CCC)C(=O)Cc1c(nc2c(N)cccn12)-c1ccc(Cl)cc1 |
Structure |
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