Reaction Details |
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Target | Prostaglandin D2 receptor |
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Ligand | BDBM50085915 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_157788 (CHEMBL767847) |
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IC50 | >10000±n/a nM |
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Citation | Wang, Y; Wos, JA; Dirr, MJ; Soper, DL; deLong, MA; Mieling, GE; De, B; Amburgey, JS; Suchanek, EG; Taylor, CJ Design and synthesis of 13,14-dihydro prostaglandin F(1alpha) analogues as potent and selective ligands for the human FP receptor. J Med Chem43:945-52 (2000) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Prostaglandin D2 receptor |
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Name: | Prostaglandin D2 receptor |
Synonyms: | PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor |
Type: | Enzyme |
Mol. Mass.: | 40288.87 |
Organism: | Homo sapiens (Human) |
Description: | Q13258 |
Residue: | 359 |
Sequence: | MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
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BDBM50085915 |
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n/a |
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Name | BDBM50085915 |
Synonyms: | 7-{3,5-Dihydroxy-2-[3-hydroxy-4-(thiazol-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid | CHEMBL173811 |
Type | Small organic molecule |
Emp. Form. | C19H31NO5S2 |
Mol. Mass. | 417.583 |
SMILES | OC(CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CSc1nccs1 |
Structure |
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