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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2b | ||
| Ligand | BDBM50207816 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_4794 (CHEMBL618339) | ||
| Ki | 7.75±n/a nM | ||
| Citation |  Kim, YC; Ji, X; Melman, N; Linden, J; Jacobson, KA Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. J Med Chem43:1165-72 (2000) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2b | |||
| Name: | Adenosine receptor A2b | ||
| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 36341.22 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 332 | ||
| Sequence: |
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| BDBM50207816 | |||
| n/a | |||
| Name | BDBM50207816 | ||
| Synonyms: | CHEMBL273094 | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide (xanthine amine congenere, XAC) | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide(XAC) | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide | N-(2-aminoethyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide | XAC | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H28N6O4 | ||
| Mol. Mass. | 428.4848 | ||
| SMILES | CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)NCCN)cc1 | ||
| Structure | 
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