| Reaction Details |
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 | Report a problem with these data |
| Target | rRNA adenine N-6-methyltransferase |
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| Ligand | BDBM50086580 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_67532 |
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| Ki | >100000±n/a nM |
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| Citation |  Hanessian, S; Sgarbi, PW Design and synthesis of mimics of S-adenosyl-L-homocysteine as potential inhibitors of erythromycin methyltransferases. Bioorg Med Chem Lett10:433-7 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| rRNA adenine N-6-methyltransferase |
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| Name: | rRNA adenine N-6-methyltransferase |
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| Synonyms: | ERM_STREE | ErmAM | Macrolide-lincosamide-streptogramin B resistance protein | erm |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28804.82 |
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| Organism: | Streptococcus pneumoniae |
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| Description: | ChEMBL_67532 |
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| Residue: | 245 |
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| Sequence: | MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELD
SHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIPYHLSTQIIKKVVFESHAS
DIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHTT
DVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTITYEQVLSIFNSYLL
FNGRK
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| BDBM50086580 |
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| n/a |
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| Name | BDBM50086580 |
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| Synonyms: | (3R,4S,5S)-2-[4-Amino-6-(indan-2-ylamino)-[1,3,5]triazin-2-ylmethyl]-5-phenylsulfanylmethyl-tetrahydro-furan-3,4-diol | CHEMBL136759 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27N5O3S |
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| Mol. Mass. | 465.568 |
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| SMILES | Nc1nc(CC2O[C@H](CSc3ccccc3)[C@@H](O)[C@H]2O)nc(NC2Cc3ccccc3C2)n1 |
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| Structure | 
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