| Reaction Details |
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 | Report a problem with these data |
| Target | AMP deaminase 1 |
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| Ligand | BDBM50087311 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_31893 (CHEMBL640310) |
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| Ki | 20000±n/a nM |
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| Citation |  Bookser, BC; Kasibhatla, SR; Appleman, JR; Erion, MD AMP deaminase inhibitors. 2. Initial discovery of a non-nucleotide transition-state inhibitor series. J Med Chem43:1495-507 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| AMP deaminase 1 |
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| Name: | AMP deaminase 1 |
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| Synonyms: | AMP deaminase 1 (hAMPD1) | AMP deaminase isoform M | AMPD1 | AMPD1_HUMAN | Myoadenylate deaminase |
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| Type: | Protein |
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| Mol. Mass.: | 90225.27 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 780 |
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| Sequence: | MNVRIFYSVSQSPHSLLSLLFYCAILESRISATMPLFKLPAEEKQIDDAMRNFAEKVFAS
EVKDEGGRQEISPFDVDEICPISHHEMQAHIFHLETLSTSTEARRKKRFQGRKTVNLSIP
LSETSSTKLSHIDEYISSSPTYQTVPDFQRVQITGDYASGVTVEDFEIVCKGLYRALCIR
EKYMQKSFQRFPKTPSKYLRNIDGEAWVANESFYPVFTPPVKKGEDPFRTDNLPENLGYH
LKMKDGVVYVYPNEAAVSKDEPKPLPYPNLDTFLDDMNFLLALIAQGPVKTYTHRRLKFL
SSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYQIDA
DRVVYSTKEKNLTLKELFAKLKMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASEL
RDLYLKTDNYINGEYFATIIKEVGADLVEAKYQHAEPRLSIYGRSPDEWSKLSSWFVCNR
IHCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLENIFMPVFEATINPQADPELSVFLKHIT
GFDSVDDESKHSGHMFSSKSPKPQEWTLEKNPSYTYYAYYMYANIMVLNSLRKERGMNTF
LFRPHCGEAGALTHLMTAFMIADDISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFL
EYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSV
LQCGISHEEKVKFLGDNYLEEGPAGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKSTE
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| BDBM50087311 |
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| n/a |
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| Name | BDBM50087311 |
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| Synonyms: | 8-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-octanoic acid methyl ester | CHEMBL38306 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24N4O3 |
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| Mol. Mass. | 308.3761 |
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| SMILES | COC(=O)CCCCCCCn1cnc2C(O)CNC=Nc12 |c:19| |
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| Structure | 
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