| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM50087346 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30792 (CHEMBL873051) |
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| Ki | 130±n/a nM |
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| Citation |  Kasibhatla, SR; Bookser, BC; Probst, G; Appleman, JR; Erion, MD AMP deaminase inhibitors. 3. SAR of 3-(carboxyarylalkyl)coformycin aglycon analogues. J Med Chem43:1508-18 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 40910.44 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 363 |
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| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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|
|
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| BDBM50087346 |
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| n/a |
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| Name | BDBM50087346 |
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| Synonyms: | 3-[3-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-propyl]-4-methoxy-benzoic acid methyl ester | CHEMBL290770 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N4O4 |
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| Mol. Mass. | 358.3917 |
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| SMILES | COC(=O)c1ccc(OC)c(CCCn2cnc3C(O)CNC=Nc23)c1 |c:22| |
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| Structure | 
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