| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50019059 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_38610 (CHEMBL652293) |
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| Ki | 260±n/a nM |
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| Citation |  Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL Syntheses of (R)- and (S)-2- and 6-fluoronorepinephrine and (R)- and (S)-2- and 6-fluoroepinephrine: effect of stereochemistry on fluorine-induced adrenergic selectivities. J Med Chem43:1611-9 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2_CANLF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46593.67 |
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| Organism: | Canis familiaris |
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| Description: | ChEMBL_56504 |
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| Residue: | 415 |
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| Sequence: | MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIAR
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRF
HAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNS
RSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
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| BDBM50019059 |
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| n/a |
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| Name | BDBM50019059 |
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| Synonyms: | (+/-)3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol | 3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol | 3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol(2-FEPI) | CHEMBL43711 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12FNO3 |
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| Mol. Mass. | 201.1949 |
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| SMILES | CNCC(O)c1ccc(O)c(O)c1F |
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| Structure | 
|
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