| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM50087533 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_48953 |
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| Ki | 0.400000±n/a nM |
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| Citation |  Pruitt, JR; Pinto, DJ; Estrella, MJ; Bostrom, LL; Knabb, RM; Wong, PC; Wright, MR; Wexler, RR Isoxazolines and isoxazoles as factor Xa inhibitors. Bioorg Med Chem Lett10:685-9 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | F10 | FA10_RABIT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53951.21 |
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| Organism: | Oryctolagus cuniculus |
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| Description: | ChEMBL_1471174 |
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| Residue: | 490 |
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| Sequence: | MANPLHLVLLGAALAGLLLSGSSVFISRRAANDVLARTRRANSFLEELKKGNLERECMEE
NCSYEEALEVFEDREKTNEFWNKYVDGDQCESNPCQNQGTCKDGLGMYTCSCVEGYEGQD
CEPVTRKLCSLDNGGCDQFCKEEENSVLCSCASGYTLGDNGKSCISTELFPCGKVTLGRW
RRSPATNSSEGPPEAPGPEQQDDGNLTATENPFNLLDSPEPPPEDDSSSLVRIVGGQDCR
DGECPWQALLVNEENEGFCGGTILSEYHVLTAAHCLHQAKRFKVRVGDRDTEHEEGNEET
HEVEVVVKHNRFVKETYDFDIAVLRLKTPITFRRNVAPACLPQKDWAESTLMAQKTGIVS
GFGRTHEMGRLSTTLKMLEVPYVDRNSCKRSSSFTITQNMFCAGYDARPEDACQGDSGGP
HVTRFRDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIEKSMRARAVPVAEAAGTPGP
TQPTIKGSPS
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| BDBM50087533 |
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| n/a |
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| Name | BDBM50087533 |
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| Synonyms: | 3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide | CHEMBL140072 | CHEMBL153611 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H19N5O4S |
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| Mol. Mass. | 461.493 |
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| SMILES | NC(=N)c1cccc(c1)-c1nocc1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O |
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| Structure | 
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