| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 2 |
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| Ligand | BDBM50531923 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1921534 (CHEMBL4424379) |
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| IC50 | 37000±n/a nM |
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| Citation |  Lee, JW; Hirota, T; Ono, D; Honma, S; Honma, KI; Park, K; Kay, SA Chemical Control of Mammalian Circadian Behavior through Dual Inhibition of Casein Kinase I? and ?. J Med Chem62:1989-1998 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 2 |
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| Name: | Cyclin-dependent kinase 2 |
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| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33938.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24941 |
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| Residue: | 298 |
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| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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| BDBM50531923 |
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| n/a |
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| Name | BDBM50531923 |
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| Synonyms: | CHEMBL4462126 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28F3N7 |
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| Mol. Mass. | 447.4998 |
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| SMILES | CC(C1CC1)n1cnc2c(NCc3cccc(c3)C(F)(F)F)nc(NCCN(C)C)nc12 |
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| Structure | 
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