| Reaction Details |
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 | Report a problem with these data |
| Target | Plasma kallikrein |
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| Ligand | BDBM50531926 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1921543 (CHEMBL4424388) |
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| Ki | >25000±n/a nM |
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| Citation |  Wang, D; Yang, Y; Jiang, L; Wang, Y; Li, J; Andreasen, PA; Chen, Z; Huang, M; Xu, P Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides. J Med Chem62:2172-2183 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Plasma kallikrein |
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| Name: | Plasma kallikrein |
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| Synonyms: | 3.4.21.34 | Fletcher factor | KLKB1_MOUSE | Kininogenin | Klk3 | Klkb1 | Pk | Plasma kallikrein | Plasma kallikrein heavy chain | Plasma kallikrein light chain | Plasma prekallikrein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 71398.99 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_103492 |
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| Residue: | 638 |
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| Sequence: | MILFNRVGYFVSLFATVSCGCMTQLYKNTFFRGGDLAAIYTPDAQYCQKMCTFHPRCLLF
SFLAVTPPKETNKRFGCFMKESITGTLPRIHRTGAISGHSLKQCGHQISACHRDIYKGLD
MRGSNFNISKTDNIEECQKLCTNNFHCQFFTYATSAFYRPEYRKKCLLKHSASGTPTSIK
SADNLVSGFSLKSCALSEIGCPMDIFQHSAFADLNVSQVITPDAFVCRTICTFHPNCLFF
TFYTNEWETESQRNVCFLKTSKSGRPSPPIPQENAISGYSLLTCRKTRPEPCHSKIYSGV
DFEGEELNVTFVQGADVCQETCTKTIRCQFFIYSLLPQDCKEEGCKCSLRLSTDGSPTRI
TYGMQGSSGYSLRLCKLVDSPDCTTKINARIVGGTNASLGEWPWQVSLQVKLVSQTHLCG
GSIIGRQWVLTAAHCFDGIPYPDVWRIYGGILSLSEITKETPSSRIKELIIHQEYKVSEG
NYDIALIKLQTPLNYTEFQKPICLPSKADTNTIYTNCWVTGWGYTKEQGETQNILQKATI
PLVPNEECQKKYRDYVINKQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGE
GCARKDQPGVYTKVSEYMDWILEKTQSSDVRALETSSA
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| BDBM50531926 |
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| n/a |
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| Name | BDBM50531926 |
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| Synonyms: | CHEMBL4550668 |
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| Type | Small organic molecule |
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| Emp. Form. | C51H74N14O14S2 |
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| Mol. Mass. | 1171.349 |
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| SMILES | CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CSSC[C@H](NC(=O)CNC1=O)C(N)=O)NC(C)=O |r| |
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| Structure | 
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