| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, NMDA 3A |
|---|
| Ligand | BDBM50088144 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_143317 (CHEMBL753019) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Schelkun, RM; Yuen, PW; Serpa, K; Meltzer, LT; Wise, LD; Whittemore, ER; Woodward, RM Subtype-selective N-methyl-D-aspartate receptor antagonists: benzimidazalone and hydantoin as phenol replacements. J Med Chem43:1892-7 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glutamate receptor ionotropic, NMDA 3A |
|---|
| Name: | Glutamate receptor ionotropic, NMDA 3A |
|---|
| Synonyms: | Glutamate [NMDA] receptor subunit 3A | Glutamate receptors; NMDA/AMPA | Grin3a | NMD3A_RAT | NMDA receptor subunit 3A-1 (GluN3A) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 127618.95 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | Q9R1M7 |
|---|
| Residue: | 1135 |
|---|
| Sequence: | MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTT
APRAASRAQEGGRAGAQRDDPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGAE
TLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSF
LQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQL
SLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESVINITAN
LSSTKDLLSFLQVQMDNIRNSTPTMVMFGCDMDSIRQIFEMSTQFGLSPPELHWVLGDSQ
NVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCM
DVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIISSENNFFIWNLQHDPMGKPMWTR
LGSWQGGRIVMDSGIWPEQAQRHKTHFQHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAG
QLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIV
GDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTR
DTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSAL
NVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGI
HDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLD
AFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFM
DVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVHRLLL
PRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPRSKTKRVEKSRWRRWTCKTEGDSELSL
FPRSNLGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQAHQDIPLPQRRRELPASLT
TNGKADSLNVTRSSVIQELSELEKQIQVIRQELQLAVSRKTELEEYQKTNRTCES
|
|
|
|---|
| BDBM50088144 |
|---|
| n/a |
|---|
| Name | BDBM50088144 |
|---|
| Synonyms: | 1-[5-(4-Benzyl-piperidin-1-yl)-pentyl]-1,3-dihydro-benzoimidazol-2-one | CHEMBL58992 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H31N3O |
|---|
| Mol. Mass. | 377.5224 |
|---|
| SMILES | O=c1[nH]c2ccccc2n1CCCCCN1CCC(Cc2ccccc2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
