| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, NMDA 3A |
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| Ligand | BDBM50088145 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_143326 (CHEMBL752244) |
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| IC50 | 49000±n/a nM |
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| Citation |  Schelkun, RM; Yuen, PW; Serpa, K; Meltzer, LT; Wise, LD; Whittemore, ER; Woodward, RM Subtype-selective N-methyl-D-aspartate receptor antagonists: benzimidazalone and hydantoin as phenol replacements. J Med Chem43:1892-7 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor ionotropic, NMDA 3A |
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| Name: | Glutamate receptor ionotropic, NMDA 3A |
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| Synonyms: | Glutamate [NMDA] receptor subunit 3A | Glutamate receptors; NMDA/AMPA | Grin3a | NMD3A_RAT | NMDA receptor subunit 3A-1 (GluN3A) |
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| Type: | Protein |
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| Mol. Mass.: | 127618.95 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q9R1M7 |
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| Residue: | 1135 |
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| Sequence: | MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTT
APRAASRAQEGGRAGAQRDDPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGAE
TLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSF
LQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQL
SLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESVINITAN
LSSTKDLLSFLQVQMDNIRNSTPTMVMFGCDMDSIRQIFEMSTQFGLSPPELHWVLGDSQ
NVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCM
DVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIISSENNFFIWNLQHDPMGKPMWTR
LGSWQGGRIVMDSGIWPEQAQRHKTHFQHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAG
QLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIV
GDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTR
DTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSAL
NVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGI
HDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLD
AFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFM
DVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVHRLLL
PRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPRSKTKRVEKSRWRRWTCKTEGDSELSL
FPRSNLGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQAHQDIPLPQRRRELPASLT
TNGKADSLNVTRSSVIQELSELEKQIQVIRQELQLAVSRKTELEEYQKTNRTCES
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| BDBM50088145 |
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| n/a |
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| Name | BDBM50088145 |
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| Synonyms: | 3-(5-(4-benzylpiperidin-1-yl)pentyl)imidazolidine-2,4-dione | 3-[5-(4-Benzyl-piperidin-1-yl)-pentyl]-imidazolidine-2,4-dione | CHEMBL442165 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H29N3O2 |
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| Mol. Mass. | 343.4632 |
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| SMILES | Oc1c[nH]c(=O)n1CCCCCN1CCC(Cc2ccccc2)CC1 |
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| Structure | 
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