| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50532555 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1923341 (CHEMBL4426297) |
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| Ki | 3.8±n/a nM |
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| Citation |  Segala, E; Guo, D; Cheng, RK; Bortolato, A; Deflorian, F; Doré, AS; Errey, JC; Heitman, LH; IJzerman, AP; Marshall, FH; Cooke, RM Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength. J Med Chem59:6470-9 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50532555 |
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| n/a |
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| Name | BDBM50532555 |
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| Synonyms: | CHEMBL3937413 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N8O |
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| Mol. Mass. | 404.4683 |
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| SMILES | Nc1nc(NCCN2CCC(CC2)c2ccccc2)nc2nc(nn12)-c1ccco1 |
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| Structure | 
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