| Reaction Details |
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 | Report a problem with these data |
| Target | Endothelin receptor type B |
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| Ligand | BDBM50088853 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_64017 |
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| IC50 | >25000±n/a nM |
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| Citation |  Kraus, GA; Wang, X Synthesis and endothelin receptor binding activity of synthetic analogues of RES-1149-2. Bioorg Med Chem Lett10:895-7 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endothelin receptor type B |
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| Name: | Endothelin receptor type B |
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| Synonyms: | EDNRB | EDNRB_HUMAN | ENDOTHELIN B | ET-B | ETRB | Endothelin receptor ET-B | Endothelin receptor non-selective type | Endothelin receptor, ET-A/ET-B |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49664.00 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ENDOTHELIN B EDNRB HUMAN::P24530 |
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| Residue: | 442 |
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| Sequence: | MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
LKFKANDHGYDNFRSSNKYSSS
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| BDBM50088853 |
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| n/a |
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| Name | BDBM50088853 |
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| Synonyms: | (2E,4E)-Hexa-2,4-dienoic acid (5S,7aS)-1,7a-dihydroxy-1,3,5,6,7,7a-hexahydro-isobenzofuran-5-yl ester | CHEMBL173336 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H18O5 |
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| Mol. Mass. | 266.2897 |
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| SMILES | C\C=C\C=C\C(=O)O[C@H]1CC[C@@]2(O)C(O)OCC2=C1 |c:18| |
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| Structure | 
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