| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50088953 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212533 |
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| Ki | 4.4±n/a nM |
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| Citation |  Zhao, Z; Arnaiz, DO; Griedel, B; Sakata, S; Dallas, JL; Whitlow, M; Trinh, L; Post, J; Liang, A; Morrissey, MM; Shaw, KJ Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors. Bioorg Med Chem Lett10:963-6 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
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| Type: | Enzyme |
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| Mol. Mass.: | 25790.52 |
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| Organism: | Bos taurus (bovine) |
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| Description: | P00760 |
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| Residue: | 246 |
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| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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| BDBM50088953 |
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| n/a |
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| Name | BDBM50088953 |
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| Synonyms: | 3-{1-(7-Carbamimidoyl-naphthalen-2-ylmethyl)-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]-1H-benzoimidazol-2-yl}-propionamide | CHEMBL367725 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H33N7O2 |
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| Mol. Mass. | 511.618 |
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| SMILES | CC(=N)N1CCC(CC1)Oc1ccc2nc(CCC(N)=O)n(Cc3ccc4ccc(cc4c3)C(N)=N)c2c1 |
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| Structure | 
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