Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGalectin-4
LigandBDBM50533580
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1925942 (CHEMBL4429014)
Kd 210000±n/a nM
Citation Rajput, VKMacKinnon, AMandal, SCollins, PBlanchard, HLeffler, HSethi, TSchambye, HMukhopadhyay, BNilsson, UJ A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model. J Med Chem59:8141-7 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Galectin-4
Name:Galectin-4
Synonyms:Antigen NY-CO-27 | Gal-4 | L-36 lactose-binding protein | L36LBP | LEG4_HUMAN | LGALS4 | Lactose-binding lectin 4
Type:PROTEIN
Mol. Mass.:35952.28
Organism:Homo sapiens (Human)
Description:ChEMBL_716454
Residue:323
Sequence:
MAYVPAPGYQPTYNPTLPYYQPIPGGLNVGMSVYIQGVASEHMKRFFVNFVVGQDPGSDV
AFHFNPRFDGWDKVVFNTLQGGKWGSEERKRSMPFKKGAAFELVFIVLAEHYKVVVNGNP
FYEYGHRLPLQMVTHLQVDGDLQLQSINFIGGQPLRPQGPPMMPPYPGPGHCHQQLNSLP
TMEGPPTFNPPVPYFGRLQGGLTARRTIIIKGYVPPTGKSFAINFKVGSSGDIALHINPR
MGNGTVVRNSLLNGSWGSEEKKITHNPFGPGQFFDLSIRCGLDRFKVYANGQHLFDFAHR
LSAFQRVDTLEIQGDVTLSYVQI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50533580
n/a
NameBDBM50533580
Synonyms:CHEMBL4446622
TypeSmall organic molecule
Emp. Form.C32H34O14S
Mol. Mass.674.669
SMILES[H][C@]1(O[C@H](CO)[C@H](O)[C@H](OCc2cc3ccccc3oc2=O)[C@H]1O)S[C@@H]1O[C@H](CO)[C@H](O)[C@H](OCc2cc3ccccc3oc2=O)[C@H]1O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: