Reaction Details |
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Target | 5-hydroxytryptamine receptor 2A |
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Ligand | BDBM50533622 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1926090 (CHEMBL4429162) |
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Ki | 3.2±n/a nM |
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Citation | Kumar, V; Bonifazi, A; Ellenberger, MP; Keck, TM; Pommier, E; Rais, R; Slusher, BS; Gardner, E; You, ZB; Xi, ZX; Newman, AH Highly Selective Dopamine D3 Receptor (D3R) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J Med Chem59:7634-50 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 2A |
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Name: | 5-hydroxytryptamine receptor 2A |
Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
Type: | undefined |
Mol. Mass.: | 52607.65 |
Organism: | Homo sapiens (Human) |
Description: | P28223 |
Residue: | 471 |
Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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BDBM50533622 |
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n/a |
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Name | BDBM50533622 |
Synonyms: | CHEMBL4469777 |
Type | Small organic molecule |
Emp. Form. | C13H19ClN2 |
Mol. Mass. | 238.756 |
SMILES | CCc1cccc(N2CCN(C)CC2)c1Cl |
Structure |
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