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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Ligand | BDBM50500408 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1928132 (CHEMBL4431204) | ||
| Ki | 73±n/a nM | ||
| Citation |  Sarasamkan, J; Scheunemann, M; Apaijai, N; Palee, S; Parichatikanond, W; Arunrungvichian, K; Fischer, S; Chattipakorn, S; Deuther-Conrad, W; Schüürmann, G; Brust, P; Vajragupta, O Varying Chirality Across Nicotinic Acetylcholine Receptor Subtypes: Selective Binding of Quinuclidine Triazole Compounds. ACS Med Chem Lett7:890-895 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuronal acetylcholine receptor subunit alpha-7 | |||
| Name: | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Synonyms: | ACHA7_HUMAN | CHRNA7 | Cholinergic, Nicotinic Alpha7 | NACHRA7 | Neuronal acetylcholine receptor protein alpha-7 subunit | Neuronal acetylcholine receptor subunit alpha-7 (nAChR-alpha 7) | Nicotinic acetylcholine receptor alpha-7 (alpha7 nAChR) | ||
| Type: | n/a | ||
| Mol. Mass.: | 56448.33 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | CHRNA7 (NACHRA7) | ||
| Residue: | 502 | ||
| Sequence: |
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| BDBM50500408 | |||
| n/a | |||
| Name | BDBM50500408 | ||
| Synonyms: | CHEMBL3747760 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H17FN4 | ||
| Mol. Mass. | 272.3207 | ||
| SMILES | Fc1ccc(cc1)-c1cn(nn1)[C@H]1CN2CCC1CC2 |r,wD:12.13,(-3.22,5.47,;-2.65,4.39,;-1.11,4.33,;-.39,2.97,;-1.2,1.67,;-2.75,1.72,;-3.47,3.08,;-.59,.25,;.92,-.08,;1.05,-1.6,;-.35,-2.23,;-1.37,-1.07,;2.43,-2.41,;2.41,-4.03,;3.81,-4.83,;5.21,-4.01,;5.21,-2.38,;3.81,-1.57,;3.26,-2.74,;4.33,-3.38,)| | ||
| Structure | 
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