| Reaction Details |
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 | Report a problem with these data |
| Target | Triosephosphate isomerase, glycosomal |
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| Ligand | BDBM50534545 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1929124 (CHEMBL4432300) |
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| IC50 | 77000±n/a nM |
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| Citation |  Velázquez-López, JM; Hernández-Campos, A; Yépez-Mulia, L; Téllez-Valencia, A; Flores-Carrillo, P; Nieto-Meneses, R; Castillo, R Synthesis and trypanocidal activity of novel benzimidazole derivatives. Bioorg Med Chem Lett26:4377-81 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Triosephosphate isomerase, glycosomal |
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| Name: | Triosephosphate isomerase, glycosomal |
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| Synonyms: | TIM | TPIS_TRYCR | Triose-phosphate isomerase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27334.70 |
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| Organism: | Trypanosoma cruzi |
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| Description: | ChEMBL_596695 |
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| Residue: | 251 |
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| Sequence: | MASKPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCVVAPTFLHIPMTKARLTNPK
FQIAAQNAITRSGAFTGEVSLQILKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAA
GFHVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVAT
PQQAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLK
PEFVEIIEATK
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| BDBM50534545 |
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| n/a |
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| Name | BDBM50534545 |
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| Synonyms: | CHEMBL4576576 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10ClN5O5S2 |
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| Mol. Mass. | 427.843 |
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| SMILES | COC(=O)c1cc2nc(SCC(=O)Nc3ncc(s3)[N+]([O-])=O)[nH]c2cc1Cl |
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| Structure | 
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