| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
|---|
| Ligand | BDBM50090323 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_34344 |
|---|
| Ki | 670±n/a nM |
|---|
| Citation |  Patane, MA; DiPardo, RM; Newton, RC; Price, RP; Broten, TP; Chang, RS; Ransom, RW; Di Salvo, J; Nagarathnam, D; Forray, C; Gluchowski, C; Bock, MG Phenylacetamides as selective alpha-1A adrenergic receptor antagonists. Bioorg Med Chem Lett10:1621-4 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1B adrenergic receptor |
|---|
| Name: | Alpha-1B adrenergic receptor |
|---|
| Synonyms: | ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 56862.13 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35368 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
|
|
|
|---|
| BDBM50090323 |
|---|
| n/a |
|---|
| Name | BDBM50090323 |
|---|
| Synonyms: | CHEMBL289916 | N-[3-(3',4',5',6'-Tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-propyl]-2,2-di-p-tolyl-acetamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H35N3O |
|---|
| Mol. Mass. | 441.6077 |
|---|
| SMILES | Cc1ccc(cc1)C(C(=O)NCCCN1CCC(CC1)c1ccccn1)c1ccc(C)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
